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Laurence Desjardins Selected Research

Neoplasms (Cancer)

1/2021Prospective phase II study of children affected by bilateral intraocular retinoblastoma with macular involvement of both eyes or in the only preserved eye. Macular tumor control, eye preservation rate, and visual outcome.
1/2020Craniofacial second primary tumors in patients with germline retinoblastoma previously treated with external beam radiotherapy: A retrospective institutional analysis.
4/2019TREATMENT OF EXUDATIVE CIRCUMSCRIBED CHOROIDAL HEMANGIOMA: Efficacy of Fractionated Proton Therapy (20 Gray Relative Biological Effectiveness in 8 Fractions).
3/2019Correlation between RB1germline mutations and second primary malignancies in hereditary retinoblastoma patients treated with external beam radiotherapy.
10/2018[Management of uveal melanomas, guidelines for oncologists].
2/2018Intravitreal bevacizumab for neovascular glaucoma in uveal melanoma treated by proton beam therapy.
1/2017Looking for the Most Suitable Orthotopic Retinoblastoma Mouse Model in Order to Characterize the Tumoral Development.
12/2014Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
7/2014Management of idiopathic retinal vasoproliferative tumors by slit-lamp laser or endolaser photocoagulation.
3/2014Detection rate and prognostic value of circulating tumor cells and circulating tumor DNA in metastatic uveal melanoma.
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Laurence Desjardins Research Topics

Disease

29Neoplasms (Cancer)
01/2021 - 04/2002
16Retinoblastoma (Glioblastoma, Retinal)
10/2023 - 04/2002
12Melanoma (Melanoma, Malignant)
10/2019 - 08/2002
11Neoplasm Metastasis (Metastasis)
01/2021 - 07/2006
11Uveal melanoma
07/2019 - 07/2006
4Cicatrix (Scar)
10/2023 - 01/2012
4Retinal Detachment (Retinal Detachments)
02/2018 - 07/2006
3Hemangioma (Angioma)
04/2019 - 02/2009
3Neovascular Glaucoma
02/2018 - 01/2012
2Necrosis
01/2022 - 12/2008
2Glaucoma
10/2019 - 03/2019
2Rhabdomyosarcoma
11/2014 - 12/2003
1Fistula
01/2022
1Genetic Predisposition to Disease (Genetic Predisposition)
01/2020
1Cataract (Cataracts)
10/2019
1Amelanotic Melanoma (Amelanotic Melanomas)
03/2019
1Hemorrhage
04/2018
1Hypertension (High Blood Pressure)
02/2018
1Sturge-Weber Syndrome (Sturge-Kalischer-Weber Syndrome)
01/2018
1Neoplasm Micrometastasis
05/2017
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
01/2017
1Vitreous Hemorrhage
07/2014
1Macular Edema
07/2014
1Telangiectasis (Telangiectasia)
07/2014
1Epiretinal Membrane (Epiretinal Membranes)
07/2014
1Circulating Neoplastic Cells
03/2014
1Toxic Optic Neuropathy
02/2014
1Aneuploidy (Aneuploid)
10/2013
1Margins of Excision
04/2013
1Sympathetic Ophthalmia (Sympathetic Uveitis)
08/2012
1Inflammation (Inflammations)
01/2012
1Residual Neoplasm
01/2012
1Corneal Diseases (Corneal Disease)
12/2011
1Adenoid Cystic Carcinoma (Cylindroma)
11/2011
1Keratoconus
08/2011
1Hearing Loss (Hearing Impairment)
05/2009
1High-Frequency Hearing Loss
05/2009
1Ototoxicity
05/2009
1Sarcoma (Soft Tissue Sarcoma)
08/2006
1Second Primary Neoplasms (Neoplasms, Second)
06/2006

Drug/Important Bio-Agent (IBA)

10Protons (Proton)IBA
07/2019 - 07/2006
6Retinaldehyde (Retinal)IBA
01/2021 - 07/2006
3Biomarkers (Surrogate Marker)IBA
05/2017 - 03/2014
3IodineIBA
12/2008 - 04/2002
2Dihydrotachysterol (AT 10)IBA
04/2016 - 01/2012
2Circulating Tumor DNAIBA
03/2014 - 07/2012
2Proteins (Proteins, Gene)FDA Link
06/2013 - 02/2011
2Carboplatin (JM8)FDA LinkGeneric
05/2009 - 08/2008
2CobaltIBA
02/2009 - 12/2008
2Etoposide (VP 16)FDA LinkGeneric
08/2008 - 12/2003
1Indicators and Reagents (Reagents)IBA
10/2023
1InterferonsIBA
01/2021
1Drug CombinationsIBA
01/2021
1Bevacizumab (Avastin)FDA Link
02/2018
1beta Subunit Luteinizing HormoneIBA
01/2018
1Melphalan (Alkeran)FDA LinkGeneric
07/2017
1SuspensionsIBA
01/2017
1Alkaline PhosphataseIBA
08/2016
1EverolimusFDA Link
12/2014
1NucleotidesIBA
10/2013
1Messenger RNA (mRNA)IBA
06/2013
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
04/2013
1DNA (Deoxyribonucleic Acid)IBA
07/2012
1CytokinesIBA
01/2012
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2012
1AldehydesIBA
12/2011
1Oxidoreductases (Dehydrogenase)IBA
12/2011
1RNA (Ribonucleic Acid)IBA
08/2011
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
08/2011
1Protein Tyrosine PhosphatasesIBA
02/2011
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
02/2011
1fotemustine (Muphoran)IBA
04/2010
1Neoplasm Antigens (Tumor Antigens)IBA
04/2010
1Temozolomide (Temodar)FDA LinkGeneric
04/2010
1Complementary DNA (cDNA)IBA
04/2007
1Cisplatin (Platino)FDA LinkGeneric
12/2003
1Dactinomycin (Actinomycin)FDA LinkGeneric
12/2003
1Dacarbazine (DIC)FDA LinkGeneric
12/2003
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2003

Therapy/Procedure

19Radiotherapy
01/2022 - 12/2003
13Therapeutics
03/2019 - 12/2003
10Drug Therapy (Chemotherapy)
10/2023 - 04/2002
9Proton Therapy
10/2019 - 07/2006
7Conservative Treatment
10/2023 - 08/2008
6Aftercare (After-Treatment)
06/2014 - 04/2002
5Induced Hyperthermia (Thermotherapy)
10/2023 - 04/2002
3Semiconductor Lasers
10/2023 - 04/2002
3Neoadjuvant Therapy
01/2020 - 08/2008
2Brachytherapy
10/2018 - 01/2012
2Combination Drug Therapy (Combination Chemotherapy)
11/2014 - 12/2003
2Lasers (Laser)
07/2014 - 06/2002
2Light Coagulation
07/2014 - 04/2002
1Immunotherapy
10/2018
1Injections
01/2017
1Vitrectomy
07/2014
1Slit Lamp
07/2014
1Adjuvant Chemotherapy
04/2013
1Consolidation Chemotherapy
04/2013
1Intravitreal Injections
01/2012
1Hearing Aids (Hearing Aid)
05/2009